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SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:

1. Given the following data set DEMOG:

Which selection below would be considered hard-coding?

A) if site eq 1 and sexcd ne 2 then check = 1; else if site eq 2 and sexcd ne 1 then check = 2;
B) birthdt = input(dob, mmddyy10.);
C) if sexcd eq 1 then sex = "Male"; else if sexcd eq 2 then sex = "Female";
D) if site eq 1 then sexcd = 2; else if site eq 2 then sexcd = 1;

2. Given the following vital signs data: Baseline is defined as the last non-missing value prior to Day 1.

What is the value for the change from baseline for Week 1 for Subject 2?

A) 23
B) -23
C) -11
D) 11

3. Given the following SCORE data set:

Based on the concept of Last Observation Carried Forward, what will be the value for SCORE for the Week 12 -

A) 157
B) 153
C) 152
D) missing

4. Which CDISC model is built to harmonize information collected on case report forms?

A) ADaM
B) SEND
C) SDTM
D) CDASH

5. In a Statistical Analysis Plan (SAP) the following statement is written:
To test the association between the pain intensity reported by the patient and the treatment the patient has been administered, a Cochran-Mantel-Haenszel test will be performed adjusting for the country of the patient's investigational site.
The following variables and levels are used:
- Pain intensity (PAIN): "No pain", "Mild pain", "Moderate pain", "Severe pain", "Most severe pain"
- Treatment group (TREAT): "Placebo", "Drug A", "Drug B"
- Country (COUNTRY): Eight different values.
The following program is written to perform this analysis:
proc freq data=pain;
by COUNTRY;
tables PAIN * TREAT / cmh;
run;
This code does not produce the analysis requested by the SAP.
What is wrong with this code?

A) The variable PAIN should be on the BY statement along with the variable COUNTRY.
B) The variables PAIN and TREAT should be on the BY statement, and the variable COUNTRY should be on the TABLES statement.
C) The option CMH should be on the PROC FREQ statement instead of on the TABLES statement.
D) The variable COUNTRY should be on the TABLES statement instead of the BY statement.

Solutions: